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Catatonic Schizophrenia

Catatonic schizophrenia, a rare severe mental disorder characterized by striking motor behaviour, typically involving either significant reductions in voluntary movement or hyperactivity and agitation. In some cases, the patient may remain in a state of almost complete immobility, often assuming statuesque positions. Patients may remain motionless in a rigid posture for hours or even days.

Other symptoms of catatonic schizophrenia include mutism (inability to talk), extreme compliance, stupor, and absence of almost all voluntary actions. This state of inactivity is at times preceded or interrupted by episodes of excessive motor activity and excitement, generally of an impulsive, unpredictable kind. “Catatonic schizophrenia” is a subtype of schizophrenia that includes catatonia as a key feature. Experts no longer recognize it as a diagnosis, making this name obsolete. Today, experts recognize schizophrenia as a specific disease and a spectrum of disorders. Healthcare providers regard catatonia as an important syndrome to consider and treat, especially when it happens with schizophrenia.

The American Psychiatric Association removed catatonic schizophrenia from its list of official diagnoses when updating to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), published in 2013. The World Health Organization (WHO) removed “catatonic schizophrenia” from the International Classification of Diseases when updating to the 11th edition (ICD-11) in 2019.

Symptoms

Schizophrenia typically happens in three stages and has five key symptoms. The active stage of schizophrenia is when symptoms are at their worst. The key symptoms of schizophrenia can happen regardless of whether or not catatonia is also present. Those five symptoms are:

Delusions.
Hallucinations.
Disorganized or incoherent speaking.
Disorganized or unusual movements.
Negative symptoms (in this context, negative means “diminished” or “reduced” instead of bad).
See our main Schizophrenia article for more about these symptoms and the stages during which they happen.

Symptoms of catatonia
Historically, experts have recognized up to 40 different symptoms that can happen with catatonia. The DSM-5 narrows that list to 12 symptoms.

Agitation. This means a person acts upset or irritable for no clear reason. It only counts as a symptom of catatonia if it happens and isn’t a response to something around the person having it.

Catalepsy (pronounced “cat-ah-lep-see”). This is when a person holds a position in which someone places them (you can still move them around to make them take on a new pose).

Echolalia (pronounced “eck-oh-la-lee-ah”). This is when a person echoes sounds or words that someone else makes.

Echopraxia (pronounced “eck-oh-prax-ee-ah”). This is when a person mimics or mirrors someone else’s movements or behaviors.

Grimacing. This is holding the same facial expression, usually with stiff or tense facial muscles. Sometimes, it can take the form of smiling in inappropriate contexts.

Mannerism. This is when a person acts out motions or movements that are usually seen as normal, but does them in an unusual and exaggerated way.

Mutism (pronounced “mew-tism”). This is when a person is either very or totally quiet (this is only a symptom if the person doesn’t have another condition, such as aphasia, to explain why they aren’t speaking).

Negativism (pronounced “neg-uh-tiv-ism”). This means a person doesn’t react to something happening around them or actively resists what’s happening around them for no rational reason.

Posturing. This is when a person holds a specific position, which would often be uncomfortable to people who aren’t experiencing catatonia. In contrast to catalepsy, this doesn’t involve being placed in the position by another person.

Stereotypy (pronounced “stair-ee-oh-type-ee”). These are repetitive movements that don’t seem to have a purpose. They can include finger-play and patting/rubbing one’s body.

Stupor (pronounced “stoop-er”). This is when a person is awake but doesn’t respond to what’s happening around them. People with catatonia often don’t respond to painful stimuli such as being pinched.

Waxy flexibility. This is when a person puts up some slight, even push-back or resistance to any attempt to change their position. Then their muscles slowly release and their limbs bend like a warm candle.

While people who show signs of catatonia may not react to what’s happening around them, many of them are aware of what’s happening. Research shows that people who had catatonia symptoms often remember what happened to and around them, even though they showed little or no reaction to their surroundings.

Shifts in activity level
While schizophrenia happens in phases, the involvement of catatonia often changes how the condition progresses. Most cases of schizophrenia with catatonia develop and get worse quickly.

Catatonia can also involve different levels of activity. Some people with catatonia will stay nonresponsive to the world around them for a time, but then, will shift to a much higher level of activity. In some cases, these shifts in activity level include behavior that’s impulsive or even dangerous to the person themselves or to those around them.

Treatment Options

Schizophrenia is usually treatable, though not curable. Medications are usually the main form of treatment for schizophrenia. However, when this condition also involves catatonia, different treatments are required.

There are two main ways to treat schizophrenia that’s currently causing catatonia:

Medications:
A specific class of medication is usually the first line of treatment for schizophrenia with catatonia. Benzodiazepines (pronounced “ben-zoh-die-az-ep-eens”), which can also treat severe anxiety and panic or seizures, are often very effective at reversing the effects of catatonia. Antipsychotics, which are the mainstay of treatment for schizophrenia, are typically avoided in people with acute catatonia due to their potential to worsen catatonia.

Electroconvulsive therapy (ECT):
This treatment involves sending a mild electrical current through your skin and skull and into a part of your brain. This current causes a brief seizure and changes in brain activity. Unlike how some movies and TV shows portray it, this treatment happens while a person is under anesthesia, so it’s painless. This treatment is both safe and very effective for treating catatonia symptoms. It’s usually a second-line treatment except in very severe cases.

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